The maximum frequency of operation for the 74HC4067DB,118 is 10 MHz.
Yes, the 74HC4067DB,118 can be used as a level shifter, but it's not recommended as it's primarily designed as an analog multiplexer/demultiplexer.
To ensure signal integrity, use proper PCB layout techniques, such as keeping signal traces short and away from noise sources, and using termination resistors if necessary.
No, the 74HC4067DB,118 is not designed to handle analog signals that exceed the VCC supply voltage. Ensure that the analog signal voltage does not exceed VCC + 0.5V.
The recommended power-on sequence is to apply VCC before applying any analog signals or control signals to the device.