The maximum frequency of operation for the CD74HC244E is 40 MHz.
Yes, the CD74HC244E is compatible with 5V systems, but it's recommended to use a voltage regulator to ensure a stable 5V supply.
The output enable (OE) pin should be connected to a logic low (GND) to enable the outputs. If left unconnected, the OE pin will float high, disabling the outputs.
The CD74HC244E can sink or source up to 25 mA per output pin.
Yes, the CD74HC244E is compatible with 3.3V systems, but the output voltage will be limited to 3.3V.