The maximum frequency of operation for the CD74HCT241E is 50 MHz.
Yes, the CD74HCT241E is compatible with 5V systems, but it's recommended to use a voltage regulator to ensure a stable 4.5V to 5.5V supply voltage.
It's recommended to power up the VCC pin first, followed by the input signals, and then the output enable (OE) pin. During power-down, reverse the sequence.
The CD74HCT241E can drive up to 50 pF of capacitive load per output pin.
The CD74HCT241E is rated for operation up to 125°C, but it's recommended to derate the device for high-temperature applications to ensure reliability.