The maximum operating temperature range for CY7C251-45DMB is -40°C to +85°C.
Cypress provides a Clock Domain Crossing (CDC) application note (AN54445) that provides guidelines and examples for implementing CDC with CY7C251-45DMB.
The recommended power-up sequence for CY7C251-45DMB is to power up VCC first, followed by VCCIO, and then apply the clock signal.
Cypress recommends using synchronizers or FIFOs to handle metastability issues with CY7C251-45DMB. Additionally, the device has built-in features such as asynchronous clock domains and clock enable signals to help mitigate metastability issues.
The maximum frequency for the clock input of CY7C251-45DMB is 200 MHz.