A 4-layer PCB with a solid ground plane and a separate power plane is recommended. Keep the analog and digital sections separate, and use a star-grounding scheme to minimize noise. TI provides a recommended PCB layout in the datasheet.
Use TI's PLL Loop Filter Design Tool or a similar tool to optimize the loop filter design. The tool helps calculate the component values for the loop filter based on the desired PLL bandwidth, phase margin, and other parameters.
Power up the device in the following sequence: VCC, AVCC, DVCC, and then the input clock. This ensures that the internal voltage regulators are powered up correctly and the device is properly initialized.
Use a combination of oscilloscope measurements, spectrum analyzer measurements, and debug registers to troubleshoot issues. Check the PLL lock detect output, clock output, and debug registers to identify the source of the issue.
The LMX2492QRTWRQ1 has a maximum junction temperature of 150°C. Ensure good thermal conductivity between the device and the PCB, and use thermal vias to dissipate heat. Follow TI's thermal design guidelines and use thermal simulation tools to optimize the design.