A 4-layer PCB with a solid ground plane and a separate power plane is recommended. Keep the analog and digital grounds separate and connect them at a single point. Use a 0.1uF decoupling capacitor between VCC and GND, and a 10uF capacitor between VCC and AVCC.
Use a proper termination scheme for the differential pairs, and ensure the clock signal is properly terminated. Use a common mode filter or a common mode choke to reduce EMI. Implement a robust clocking scheme, and consider using a clock buffer or a clock generator.
The SN65176BDR has a thermal pad that must be connected to a solid ground plane for heat dissipation. Ensure good airflow around the device, and consider using a heat sink or a thermal interface material. Operate the device within the recommended temperature range (-40°C to 85°C).
Power up the device in the following sequence: VCC, AVCC, and then the input signals. Ensure the power supplies are stable and within the recommended voltage range before applying input signals. Use a power-on reset circuit to ensure a clean power-up sequence.
Use ESD protection devices, such as TVS diodes or ESD arrays, on the input lines to protect against electrostatic discharge. Ensure the PCB design includes a clear path for ESD currents to flow to ground. Handle the device by the body or use an anti-static wrist strap to prevent ESD damage.