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The SN65LV1224BDBR can support clock frequencies up to 100 MHz.
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To ensure signal integrity, use a low-impedance PCB design, keep signal traces short, and use termination resistors as recommended in the datasheet.
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Yes, the SN65LV1224BDBR is compatible with 3.3V systems, but ensure that the VCC supply voltage is within the recommended range of 2.7V to 3.6V.
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Power sequencing is critical; ensure that VCC is applied before the clock signal, and that the clock signal is stable before applying data signals.
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Use a symmetrical layout, keep clock and data signals separate, and use a ground plane to minimize noise and crosstalk.