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The TCA9517 can support I2C bus frequencies up to 400 kHz.
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Yes, the TCA9517 can be used in a multi-master I2C bus configuration, but it requires external circuitry to prevent bus contention.
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The TCA9517 does not support clock stretching, so it is not suitable for use with I2C devices that require clock stretching.
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The TCA9517 can drive I2C buses with capacitances up to 400 pF.
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Yes, the TCA9517 can be used to extend the distance of an I2C bus by repeating the I2C signals and providing a higher drive current.