A good thermal design should include a solid ground plane, thermal vias under the device, and a heat sink if possible. Refer to the TI application note 'TPA6203A1 PCB Layout Guidelines' for more information.
To ensure stability, follow the recommended component values and PCB layout guidelines. Also, make sure to decouple the power supply lines with capacitors and use a low-ESR capacitor for the bootstrap capacitor (C2).
The maximum power dissipation of the TPA6203A1DRB is dependent on the ambient temperature and the thermal resistance of the PCB. Refer to the datasheet's thermal characteristics table for more information.
While it's possible to use a lower value for C2, it's not recommended as it may affect the amplifier's stability and performance. The recommended value is 10uF, but you can use a higher value if needed.
Use a voltage regulator to regulate the power supply voltage, and consider adding overvoltage protection (OVP) and electrostatic discharge (ESD) protection circuits to prevent damage to the amplifier.