The TPS2053ADR can drive up to 10,000 pF of capacitive load, but it's recommended to limit it to 4,700 pF for optimal performance.
To ensure fast turn-on, make sure to use a pull-up resistor on the EN pin, and consider adding a capacitor between the EN pin and GND to filter out noise.
No, the TPS2053ADR is a low-side switch, meaning it can only switch the ground connection of a load. If you need to switch the high side, consider using a different device, such as the TPS2063ADR.
The TPS2053ADR can operate with input voltages as low as 2.7V, but the output voltage will be limited to 2.5V. For full output voltage range, use an input voltage of at least 3.5V.
Use a flyback diode (such as a 1N4007) in parallel with the load to absorb back-EMF. You can also add a series resistor to the load to reduce the inductive kickback.